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A novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces sp.
- Authors
- Shin, Choonshik; Lim, Haeyoung; Moon, Sangik; Kim, Seunghyun; Yong, Yeonjoong; Kim, Bum-Joon; Lee, Chul-Hoon; Lim, Yoongho
- Issue Date
- Nov-2006
- Publisher
- Pergamon Press Ltd.
- Keywords
- antiproliferative; Streptomyces sp; phenylpyridineylbutenol
- Citation
- Bioorganic & Medicinal Chemistry Letters, v.16, no.21, pp 5643 - 5645
- Pages
- 3
- Indexed
- SCIE
SCOPUS
- Journal Title
- Bioorganic & Medicinal Chemistry Letters
- Volume
- 16
- Number
- 21
- Start Page
- 5643
- End Page
- 5645
- ISSN
- 0960-894X
1464-3405
- Abstract
- A novel compound showing antiproliferative effect was isolated from Streptomyces sp. Its structure was determined based on the interpretation of the NMR spectra, and its conformation was elucidated using molecular modeling and 2D NOESY. It was determined to be (E)-4-phenyl-3-(pyridine-2-yl)but-2-en-1-ol. (c) 2006 Elsevier Ltd. All rights reserved.
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