LIF 공초점 현미경을 이용한 장애물이 있는 Y-채널 마이크로믹서의 최적설계 평가

Abstract

Owing to the extremely small device and velocity scale, mixing in microchannel proceeds very slowly by way of molecular diffusion transport. Thus mixing enhancement becomes a central issue in microfluidics for biomedical and chemical applications. In this work, we evaluate the simulation result of optimization procedure through experiment and fabrication. In efficient micromixer design, it is essential to evaluate mixing efficiency with good precision. Mixing efficiency for Y-channel micromixer is measured by fluorescence intensity using LIF(Laser Induced Fluorescence) Confocal Microscope. The Y-channel micromixers are fabricated with polydimethylsiloxane(PDMS). Nile Blue A is injected into the micromixer as a fluorescence dye for measuring of fluorescence intensity by He/Ne laser. Throughout the experiments and computer simulation, accurate mixing efficiency evaluation process for a PDMS Y-channel micromixer is established.