HPLC method for the pharmacokinetics study of acemetacin in human plasma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ban, E | - |
dc.contributor.author | Cho, JH | - |
dc.contributor.author | Jang, DJ | - |
dc.contributor.author | Piao, XL | - |
dc.contributor.author | Kim, JK | - |
dc.contributor.author | Ji, JP | - |
dc.contributor.author | Kim, CK | - |
dc.date.accessioned | 2021-06-24T00:37:55Z | - |
dc.date.available | 2021-06-24T00:37:55Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2005-02 | - |
dc.identifier.issn | 1082-6076 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/46513 | - |
dc.description.abstract | A reproducible and specific high performance liquid chromatography (HPLC) method was developed to quantity plasma levels of acemetacin and its metabolite, indometacin in order to conduct a pharmacokinetics study. Plasma samples were prepared by liquid-liquid extraction using ethyl acetate.- Extracted samples were analyzed on a reverse-phase C-18 column with a mobile phase consisting of 20mM phosphate buffer (pH 2.9) and acetonitrile (60:40, v/v) and UV detection at 254nm. Using this method, the phannacokinctics study was carried out on eight volunteers after a single oral administration. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS INC | - |
dc.title | HPLC method for the pharmacokinetics study of acemetacin in human plasma | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, JK | - |
dc.identifier.doi | 10.1081/JLC-200058377 | - |
dc.identifier.scopusid | 2-s2.0-20844444002 | - |
dc.identifier.wosid | 000230093000014 | - |
dc.identifier.bibliographicCitation | JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, v.28, no.10, pp.1593 - 1604 | - |
dc.relation.isPartOf | JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | - |
dc.citation.title | JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | - |
dc.citation.volume | 28 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1593 | - |
dc.citation.endPage | 1604 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | LIQUID-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | INDOMETHACIN | - |
dc.subject.keywordAuthor | acemetacin | - |
dc.subject.keywordAuthor | indometacin | - |
dc.subject.keywordAuthor | high performance liquid chromatography (HPLC) | - |
dc.identifier.url | https://www.tandfonline.com/doi/full/10.1081/JLC-200058377 | - |
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