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Indole Alkaloids from Tropical Sponge Hyrtios sp as Isocitrate Lyase Inhibitors
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, Seung-Il | - |
| dc.contributor.author | Lee, Yeon-Ju | - |
| dc.contributor.author | Won, Hoshik | - |
| dc.contributor.author | Oh, Ki-Bong | - |
| dc.contributor.author | Lee, Hyi-Seung | - |
| dc.date.accessioned | 2021-06-22T12:01:12Z | - |
| dc.date.available | 2021-06-22T12:01:12Z | - |
| dc.date.created | 2021-01-21 | - |
| dc.date.issued | 2018-06 | - |
| dc.identifier.issn | 1934-578X | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/6205 | - |
| dc.description.abstract | A new beta-carboline alkaloid, 3,4-dihydrohyrtiosulawesine (8), and fifteen known alkaloids were isolated from the tropical marine sponge Hyrtios sp. Among these known compounds, beta-ketoserotonin (10) has been isolated for the first time from a natural source. The structures of the isolated compounds were determined by spectroscopic analyses and comparison with literature values. Compound 8 displayed potent inhibitory activities against isocitrate lyase (IC50: 92.9 mu M) from Candida albicans. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | Natural Product Communications | - |
| dc.title | Indole Alkaloids from Tropical Sponge Hyrtios sp as Isocitrate Lyase Inhibitors | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Won, Hoshik | - |
| dc.identifier.doi | 10.1177/1934578x1801300608 | - |
| dc.identifier.scopusid | 2-s2.0-85048994458 | - |
| dc.identifier.wosid | 000436892800008 | - |
| dc.identifier.bibliographicCitation | Natural product communications, v.13, no.6, pp.683 - 685 | - |
| dc.relation.isPartOf | Natural product communications | - |
| dc.citation.title | Natural product communications | - |
| dc.citation.volume | 13 | - |
| dc.citation.number | 6 | - |
| dc.citation.startPage | 683 | - |
| dc.citation.endPage | 685 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Food Science & Technology | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
| dc.subject.keywordPlus | MARINE SPONGES | - |
| dc.subject.keywordPlus | GLYOXYLATE CYCLE | - |
| dc.subject.keywordPlus | BETA-CARBOLINES | - |
| dc.subject.keywordPlus | ERECTUS | - |
| dc.subject.keywordAuthor | Hyrtios sp. | - |
| dc.subject.keywordAuthor | beta-Carboline alkaloids | - |
| dc.subject.keywordAuthor | Isocitrate lyase | - |
| dc.identifier.url | https://journals.sagepub.com/doi/10.1177/1934578X1801300608 | - |
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Related Researcher
- Won, Ho shik
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY (DEPARTMENT OF CHEMICAL AND MOLECULAR ENGINEERING)