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Hypoxanthine phosphoribosyltransferase (HPRT)-deficiency is associated with impaired fertility in the female rat
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Meek, Stephen | - |
| dc.contributor.author | Sutherland, Linda | - |
| dc.contributor.author | Wei, Jun | - |
| dc.contributor.author | Sturmey, Roger | - |
| dc.contributor.author | Binas, Bert | - |
| dc.contributor.author | Clinton, Michael | - |
| dc.contributor.author | Burdon, Tom | - |
| dc.date.accessioned | 2021-06-22T06:00:07Z | - |
| dc.date.available | 2021-06-22T06:00:07Z | - |
| dc.date.issued | 2020-09 | - |
| dc.identifier.issn | 1040-452X | - |
| dc.identifier.issn | 1098-2795 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/905 | - |
| dc.description.abstract | The purine hypoxanthine plays important role in regulating oocyte maturation and early embryonic development. The enzyme hypoxanthine phosphoribosyltransferase (HPRT) recycles hypoxanthine to generate substrates for nucleotide synthesis and key metabolites, and here we show that HPRT deficiency in the rat disrupts early embryonic development and causes infertility in females. | - |
| dc.format.extent | 4 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | John Wiley & Sons Inc. | - |
| dc.title | Hypoxanthine phosphoribosyltransferase (HPRT)-deficiency is associated with impaired fertility in the female rat | - |
| dc.type | Article | - |
| dc.publisher.location | 미국 | - |
| dc.identifier.doi | 10.1002/mrd.23413 | - |
| dc.identifier.scopusid | 2-s2.0-85089870766 | - |
| dc.identifier.wosid | 000562909900001 | - |
| dc.identifier.bibliographicCitation | Molecular Reproduction and Development, v.87, no.9, pp 930 - 933 | - |
| dc.citation.title | Molecular Reproduction and Development | - |
| dc.citation.volume | 87 | - |
| dc.citation.number | 9 | - |
| dc.citation.startPage | 930 | - |
| dc.citation.endPage | 933 | - |
| dc.type.docType | Letter | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Cell Biology | - |
| dc.relation.journalResearchArea | Developmental Biology | - |
| dc.relation.journalResearchArea | Reproductive Biology | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Cell Biology | - |
| dc.relation.journalWebOfScienceCategory | Developmental Biology | - |
| dc.relation.journalWebOfScienceCategory | Reproductive Biology | - |
| dc.subject.keywordPlus | METABOLISM | - |
| dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1002/mrd.23413 | - |
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