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Smart chemistry-based nanosized drug delivery systems for systemic applications: A comprehensive review
- Authors
- Ramasamy, Thiruganesh; Ruttala, Hima Bindu; Gupta, Biki; Poudel, Bijay Kumar; Choi, Han-Gon; Yong, Chul Soon; Kim, Jong Oh
- Issue Date
- Jul-2017
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- Nanomedicine; Smart chemistry; Nanocarrier; Drug delivery
- Citation
- JOURNAL OF CONTROLLED RELEASE, v.258, pp 226 - 253
- Pages
- 28
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- JOURNAL OF CONTROLLED RELEASE
- Volume
- 258
- Start Page
- 226
- End Page
- 253
- ISSN
- 0168-3659
1873-4995
- Abstract
- This review focuses on the smart chemistry that has been utilized in developing polymer-based drug delivery systems over the past 10 years. We provide a comprehensive overview of the different functional moieties and reducible linkages exploited in these systems, and outline their design, synthesis, and application from a therapeutic efficacy viewpoint. Furthermore, we highlight the next generation nanomedicine strategies based on this novel chemistry.
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Related Researcher
- Choi, Han Gon
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)