Two dimensional array of ZnSe-ferritin for dopamine detection
- Authors
- Choi, Eun Ah; Park, Sang Joon
- Issue Date
- Jan-2014
- Publisher
- IOP PUBLISHING LTD
- Citation
- JAPANESE JOURNAL OF APPLIED PHYSICS, v.53, no.1
- Journal Title
- JAPANESE JOURNAL OF APPLIED PHYSICS
- Volume
- 53
- Number
- 1
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12960
- DOI
- 10.7567/JJAP.53.01AF03
- ISSN
- 0021-4922
- Abstract
- Less toxic zinc selenide (ZnSe) quantum dots were synthesized in the cavity of the apoferritin from horse spleen (HsAFr), and the two-dimensional ZnSe-ferritin nanodots were prepared on modified silicon surface. For utilizing the array as a biosensor, the photoluminescence (PL) spectrum change was investigated by accompanying its conjugation reaction with a neurotransmitter dopamine. When the array was conjugated with dopamine, a significant quenching of the fluorescence occurred and the PL intensity was a linear function of the dopamine concentration in the range of 0-0.6 mu M. Accordingly, the ZnSe-ferritin nanodot arrays can be employed as a useful sensing media for tiny concentration of dopamine. (C) 2014 The Japan Society of Applied Physics
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