한국약용식물의 최종당화산물 생성저해활성 검색(VII)Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (VII)
- Other Titles
- Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (VII)
- Authors
- 최소진; 김영숙; 송유진; 이윤미; 김주환; 김진숙
- Issue Date
- Dec-2012
- Publisher
- 한국생약학회
- Keywords
- Advanced glycation end products (AGEs); Diabetic complications; Korean herbal medicines
- Citation
- 생약학회지, v.43, no.4, pp.345 - 351
- Journal Title
- 생약학회지
- Volume
- 43
- Number
- 4
- Start Page
- 345
- End Page
- 351
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16860
- ISSN
- 0253-3073
- Abstract
- In this study, 49 Korean herbal medicines have been investigated with an in vitro evaluation system using glycation end products (AGEs) formation inhibitory activity. Of these, 18 herbal medicines (IC_50<50 µg/ml) were found to have significant AGEs formation inhibitory activity. Of these, five herbal medicines (IC_50<10 µg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, Mallotus japonicus (twigs and leaves), Rhus javanica (twigs and leaves), Boehmeria nivea (whole plants), Quercus acuta (stems), and Eurya japonica (stems) showed more potent inhibitory activity (approximately 9-37 fold) than the positive control aminoguanidine (IC_50=76.47 µg/ml).
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