4,4 '-Diaponeurosporene from Lactobacillus plantarum subsp. plantarum KCCP11226: Low Temperature Stress-Induced Production Enhancement and In Vitro Antioxidant Activity
- Authors
- 김미방; 정동현; 서동호; 박영서; 서명지
- Issue Date
- Jan-2021
- Publisher
- 한국미생물·생명공학회
- Keywords
- Lactobacillus plantarum subsp. plantarum; 4; 4′-diaponeurosporene; C30 carotenoid; antioxidant; low temperature
- Citation
- Journal of Microbiology and Biotechnology, v.31, no.1, pp.63 - 69
- Journal Title
- Journal of Microbiology and Biotechnology
- Volume
- 31
- Number
- 1
- Start Page
- 63
- End Page
- 69
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80318
- DOI
- 10.4014/jmb.2010.10022
- ISSN
- 1017-7825
- Abstract
- Carotenoids, which have biologically beneficial effects and occur naturally in microorganisms and plants, are pigments widely applied in the food, cosmetics and pharmaceutical industries. The compound 4,4′-diaponeurosporene is a C30 carotenoid produced by some Lactobacillus species, and Lactobacillus plantarum is the main species producing it. In this study, the antioxidant activity of 4,4′-diaponeurosporene extracted from L. plantarum subsp. plantarum KCCP11226 was examined.
Maximum carotenoid content (0.74 ± 0.2 at A470) was obtained at a relatively low temperature (20°C).
The DPPH radical scavenging ability of 4,4′-diaponeurosporene (1 mM) was approximately 1.7-fold higher than that of butylated hydroxytoluene (BHT), a well-known antioxidant food additive. In addition, the ABTS radical scavenging ability was shown to be 2.3- to 7.5-fold higher than that of BHT at the range of concentration from 0.25 mM to 1 mM. The FRAP analysis confirmed that 4,4′- diaponeurosporene (0.25 mM) was able to reduce Fe3+ by 8.0-fold higher than that of BHT.
Meanwhile, 4,4′-diaponeurosporene has been confirmed to be highly resistant to various external stresses (acid/bile, high temperature, and lysozyme conditions). In conclusion, L. plantarum subsp.
plantarum KCCP11226, which produces 4,4′-diaponeurosporene as a functional antioxidant, may be a potentially useful strain for the development of functional probiotic industries.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 바이오나노대학 > 식품생물공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80318)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.