Cancer Cell Detection on the Surface of Top-Gated Monolayer Graphene via Raman Spectroscopy
DC Field | Value | Language |
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dc.contributor.author | Nanda, S.S. | - |
dc.contributor.author | Kaushal, S. | - |
dc.contributor.author | Shin, Yong | - |
dc.contributor.author | Yun, Kyusik | - |
dc.contributor.author | An, Seong Soo A. | - |
dc.contributor.author | Hembram, K.P.S.S. | - |
dc.contributor.author | Papaefthymiou, G.C. | - |
dc.contributor.author | Yi, Dong Kee | - |
dc.date.available | 2021-03-24T00:40:34Z | - |
dc.date.created | 2021-02-04 | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 2576-6422 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80535 | - |
dc.description.abstract | A label-free biosensor is described based on the Raman spectroscopic signatures of monolayer graphene, which are modified in the compartment of cancer cells because of electron-phonon coupling in monolayer graphene. Specifically, the Raman spectra of electrostatically gated monolayer graphene on SiO2/Si substrates, in the voltage range from 0 to 5 V, were studied in the absence and the presence of cancer cells. Density functional theory simulations afforded a correlation between cancer cells and the observed Raman spectra, through the regulation of the intensities of the G and 2D Raman vibrational modes with applied voltage. The C-H and N-H bonds of phenylalanine enabled the detection of this biosensing activity. Significantly, this detection can be carried out even in the absence of cancer cell-culturing steps. © | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | American Chemical Society | - |
dc.relation.isPartOf | ACS Applied Bio Materials | - |
dc.title | Cancer Cell Detection on the Surface of Top-Gated Monolayer Graphene via Raman Spectroscopy | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000620346200034 | - |
dc.identifier.doi | 10.1021/acsabm.0c01377 | - |
dc.identifier.bibliographicCitation | ACS Applied Bio Materials, v.4, no.2, pp.1493 - 1498 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85099951729 | - |
dc.citation.endPage | 1498 | - |
dc.citation.startPage | 1493 | - |
dc.citation.title | ACS Applied Bio Materials | - |
dc.citation.volume | 4 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Yun, Kyusik | - |
dc.contributor.affiliatedAuthor | An, Seong Soo A. | - |
dc.type.docType | Article in Press | - |
dc.subject.keywordAuthor | biosensor | - |
dc.subject.keywordAuthor | cancer cell | - |
dc.subject.keywordAuthor | DFT | - |
dc.subject.keywordAuthor | graphene | - |
dc.subject.keywordAuthor | Raman spectroscopy | - |
dc.subject.keywordPlus | Amino acids | - |
dc.subject.keywordPlus | Cytology | - |
dc.subject.keywordPlus | Density functional theory | - |
dc.subject.keywordPlus | Diseases | - |
dc.subject.keywordPlus | Electron-phonon interactions | - |
dc.subject.keywordPlus | Graphene | - |
dc.subject.keywordPlus | Monolayers | - |
dc.subject.keywordPlus | Raman scattering | - |
dc.subject.keywordPlus | Raman spectroscopy | - |
dc.subject.keywordPlus | Silica | - |
dc.subject.keywordPlus | Silicon | - |
dc.subject.keywordPlus | Applied voltages | - |
dc.subject.keywordPlus | Cancer cell detection | - |
dc.subject.keywordPlus | Density functional theory simulations | - |
dc.subject.keywordPlus | Electron phonon couplings | - |
dc.subject.keywordPlus | Label-free biosensor | - |
dc.subject.keywordPlus | Raman spectroscopic | - |
dc.subject.keywordPlus | Vibrational modes | - |
dc.subject.keywordPlus | Voltage ranges | - |
dc.subject.keywordPlus | Cells | - |
dc.description.journalRegisteredClass | scopus | - |
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