Oral administration of H. syriacus L. flower ameliorates photoaging and dryness in UVB-irradiated skin무궁화 꽃 추출물 경구투여에 의한 피부 광노화 및 건조증 개선에 관한 효과
- Other Titles
- 무궁화 꽃 추출물 경구투여에 의한 피부 광노화 및 건조증 개선에 관한 효과
- Authors
- 양정은; 서슬아; 강민철; 윤다혜; 임태준; 황은선; 원경화; 이택환; 김선여
- Issue Date
- Aug-2021
- Publisher
- 한국식품과학회
- Keywords
- H. syriacus L. flower; anti-aging; moisturizing; functional food; hairless mice
- Citation
- 한국식품과학회지, v.53, no.4, pp.399 - 407
- Journal Title
- 한국식품과학회지
- Volume
- 53
- Number
- 4
- Start Page
- 399
- End Page
- 407
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/82501
- DOI
- 10.9721/KJFST.2021.53.4.399
- ISSN
- 0367-6293
- Abstract
- Wrinkle formation and dryness are the most well-known symptoms of skin aging. This study investigated skin anti-aging and moisturizing effects of Mugunghwa (Hibiscus syriacus L.), the national flower of Korea. The effect of H.
syriacus L. flower extract was examined in skin cells originating from humans in vitro and in hairless mice exposed to UVB in vivo. The in vivo study results showed that skin hydration-related factors such as involucrin, filaggrin, HAS1, HYAL1, and matrix metalloproteinase-I (a primary skin photoaging factor) were regulated by H. syriacus L. Additionally, epidermal thickness and collagen disruption, which resulted in wrinkle formation and skin dryness, were ameliorated by oral administration of H. syriacus L. These results indicate that H. syriacus L. flowers can play important roles in preventing aging and promoting skin moisturizing.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 약학대학 > 약학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/82501)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.