Efficacy of black rice extract on obesity in obese postmenopausal women: a 12-week randomized, double-blind, placebo-controlled preliminary clinical trial
- Authors
- Jung, Ah Jin; Sharma, Anshul; Lee, Sung-Hyen; Lee, Sung-Joon; Kim, Jung-Hwan; Lee, Hae-Jeung
- Issue Date
- Dec-2021
- Publisher
- Lippincott Williams & Wilkins Ltd.
- Keywords
- Anthocyanins; Antiobesity; Body composition; Body fat; Body mass index; Total fat
- Citation
- Menopause, v.28, no.12, pp.1391 - 1399
- Journal Title
- Menopause
- Volume
- 28
- Number
- 12
- Start Page
- 1391
- End Page
- 1399
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/83553
- DOI
- 10.1097/GME.0000000000001862
- ISSN
- 1072-3714
- Abstract
- OBJECTIVES: Postmenopausal obesity is a paramount health concern among older women. Black rice is a well-known pigmented rice variety with a higher anthocyanin content. Both in vitro and in vivo studies have demonstrated the effects of black rice on obesity. The present study aimed to investigate the effects of black rice extract (BRE) on obesity among obese postmenopausal women from Korea. METHODS: This was a 12-week, randomized, double-blind, placebo-controlled preliminary clinical trial. The participants were postmenopausal women who had stopped menstruating for more than a year. Specifically, 105 participants were randomly assigned to the BRE (1 g/d) or placebo (maltodextrin, 1 g/d) group. RESULTS: Eighty-eight participants completed the study, 47 in the intervention group and 41 in the placebo group. At the study endpoint, dual-energy x-ray absorptiometry assessment showed that the BRE group had a significantly lower trunk fat (P = 0.04), total fat (P = 0.04), and total body fat percentage (P = 0.04) than did the placebo group. The body fat percentage (P = 0.04) was lower in the BRE group with marginal significance, and there were no significant differences in anthropometric measures such as weight, body mass index, waist circumference, or waist-to-hip ratio estimated by bioelectrical impedance analysis. CONCLUSION: BRE supplementation for 12 weeks seems to be effective in reducing fat accumulation in postmenopausal women. Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The North American Menopause Society.
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