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Showing results 1 to 19 of 19

SCISCIESCOPUS
A novel three-dimensional model system for keloid study: Organotypic multicellular scar model

Lee, Won Jai; Choi, Il-Kyu; Lee, Ju Hee; Kim, Yong Oock; Yun, Chae-Ok

ArticleIssue Date2013CitationWound Repair and Regeneration, v.21, no.1, pp 155 - 165PublisherBlackwell Publishing Inc.
SCISCIESCOPUS
Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids

Lee, Won Jai; Ahn, Hyo Min; Roh, Hyun; Na, Youjin; Choi, Il-Kyu; Lee, Ju Hee; Kim, Yong Oock; Lew, Dae Hyun; Yun, Chae-Ok

ArticleIssue Date2015CitationExperimental Dermatology, v.24, no.8, pp 591 - 597PublisherBlackwell Publishing Inc.
Decorin-Expressing Adenovirus Decreases Collagen Synthesis and Upregulates the MMP Expression in Keloids; Implication for Reversing Pathologic FibrosisGo to Link

Lee, Won Jai; Ahn, Hyo-Min; Roh, Hyun; Lee, Ju Hee; Choi, Il-Kyu; Kim, Yong Oock; Lew, Dae Hyun; Yun, Chae-Ok

ConferenceIssue Date2014Citation17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), pp.S31PublisherThe American Society of Gene & Cell TherapyPlaceUS; Washington, DC
SCISCIESCOPUS
Decoy Wnt receptor (sLRP6E1E2)-expressing adenovirus induces antifibrotic effect via inhibition of Wnt and TGF-beta signalingGo to Linkopen access

Lee, Won Jai; Lee, Jung-Sun; Ahn, Hyo Min; Na, Youjin; Yang, Chae Eun; Lee, Ju Hee; Hong, JinWoo; Yun, Chae-Ok

ArticleIssue Date2017CitationScientific Reports, v.7PublisherNature Publishing Group
SCISCIE
Effect of Decorin-Expressing Adenovirus on Pathologic Fibrosis; Decreased Collagen Synthesis and Elevated MMP Expression

Ahn, Hyo Min; Na, Youjin; Choi, Il-Kyu; Lee, Won Jai; Kim, Yong Oock; Lee, Ju Hee; Lew, Dae Hyun; Roh, Hyun; Yun, Chae-Ok

ArticleIssue Date2015CitationMolecular Therapy, v.23, pp S130 - S131PublisherNature Publishing Group
SCISCIE
Effects of Alginate Gel-Encapsulated Adenoviruses Expressing Relaxin on Scar Remodeling in a Pig Model

Yun, In Sik; Lee, Won Jai; Kim, Yong Oock; Kang, Eun Hye; Choi, Il-Kyu; Kim, Hoguen; Chung, Kee Yang; Han, Seung-Kyu; Lew, Dae Hyun; Rah, Dong Kyun, et al.

ArticleIssue Date2014CitationMolecular Therapy, v.22, pp S31 - S31PublisherNature Publishing Group
SCISCIESCOPUS
Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis

Lee, Won Jai; Park, Ji Hun; Shin, Jung U.; Noh, Hyun; Lew, Dae Hyun; Yang, Woo Ick; Yun, Chae Ok; Lee, Kwang Hoon; Lee, Ju Hee

ArticleIssue Date2015CitationWound Repair and Regeneration, v.23, no.3, pp 435 - 442PublisherBlackwell Publishing Inc.
SCIESCOPUS
Ethyl Pyruvate Decreases Collagen Synthesis and Upregulates MMP Activity in Keloid Fibroblasts and Keloid SpheroidsGo to Linkopen access

Baek, Wooyeol; Park, Seonghyuk; Lee, Youngdae; Roh, Hyun; Yun, Chae-Ok; Roh, Tai Suk; Lee, Won Jai

ArticleIssue Date2024CitationInternational Journal of Molecular Sciences, v.25, no.11, pp 1 - 15PublisherMultidisciplinary Digital Publishing Institute (MDPI)
SCISCIESCOPUS
Extramarginal excision is preferable for hypertrophic scars

Shin, Jung U.; Park, Jihun; Lee, Ju Hee; Lee, Kwnag Hoon; Kim, Yong-Ook; Yun, Chae-Ok; Lee, Won Jai

ArticleIssue Date2014CitationInternational Journal of Dermatology, v.53, no.9, pp 1138 - 1144PublisherBlackwell Publishing Inc.
SCISCIESCOPUS
Gene Therapy Using Hepatocyte Growth Factor Expressing Adenovirus Improves Skin Flap Survival in a Rat ModelGo to Link

Rah, Dong Kyun; Yun, In Sik; Yun, Chae-Ok; Lee, Sae Bin; Lee, Won Jai

ArticleIssue Date2014CitationJournal of Korean Medical Science, v.29, pp S228 - S236Publisher대한의학회
SCIESCOPUS
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model

Lee, Won Jai; Lee, Ju Hee; Ahn, Hyo Min; Song, Seung Yong; Kim, Yong Oock; Lew, Dae Hyun; Yun, Chae-Ok

ArticleIssue Date2015CitationPlastic and Reconstructive Surgery, v.136, no.3, pp 328e - 337ePublisherWilliams & Wilkins Co.
SCISCIESCOPUS
Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts

Jeon, Yeo Reum; Ahn, Hyo Min; Choi, Il Kyu; Yun, Chae Ok; Rah, Dong Kyun; Lew, Dae Hyun; Lee, Won Jai

ArticleIssue Date2016CitationInternational Journal of Dermatology, v.55, no.3, pp 356 - 361PublisherBlackwell Publishing Inc.
SCIE
Inhibition of Mortalin Leads to Anti-Fibrosis and Apoptosis of the Keloid SpheroidGo to Linkopen access

Ahn, Hyo Min; Lee, Won Jai; Na, Youjin; Wadhwa, Renu; Hong, JinWoo; Yun, Chae-Ok

ArticleIssue Date2018CitationMOLECULAR THERAPY, v.26, no.5, pp.333 - 333PublisherCELL PRESS
SCISCIESCOPUS
Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroidsGo to Linkopen access

Lee, Won Jai; Ahn, Hyo Min; Na, Youjin; Wadhwa, Renu; Hong, JinWoo; Yun, Chae-Ok

ArticleIssue Date2017CitationScientific Reports, v.7PublisherNature Publishing Group
SCISCIE
Organotypic Multicellular Scar Model; Innovative and Novel 3-Dimensional System for Keloid Study

Ahn, Hyo Min; Choi, Il-Kyu; Lee, Won Jai; Lee, Ju Hee; Kim, Yong Oock; Yun, Chae-Ok

ArticleIssue Date2015CitationMolecular Therapy, v.23, pp S152 - S152PublisherNature Publishing Group
SCIESCOPUS
Profibrogenic effect of high-mobility group box protein-1 in human dermal fibroblasts and its excess in keloid tissuesGo to Linkopen access

Lee, Won Jai; Song, Seung Yong; Roh, Hyun; Ahn, Hyo Min; Na, Youjin; Kim, Jihee; Lee, Ju Hee; Yun, Chae Ok

ArticleIssue Date2018CitationSCIENTIFIC REPORTS, v.8PublisherNATURE PUBLISHING GROUP
SCISCIESCOPUS
Relaxin-Expressing Adenovirus Decreases Collagen Synthesis and Up-Regulates Matrix Metalloproteinase Expression in Keloid Fibroblasts: In Vitro Experiments

Lee, Won Jai; Choi, Il-Kyu; Lee, Ju Hee; Lee, Jung-Sun; Kim, Yong Oock; Rah, Dong Kyun; Yun, Chae-Ok

ArticleIssue Date2012CitationPlastic and Reconstructive Surgery, v.130, no.3, pp 407e - 417ePublisherWilliams & Wilkins Co.
SCIESCOPUS
Wnt 3a induced endothelial-to-mesenchymal transition in human dermal microvascular endothelial cell and examined on keloid tissues

Lee, Won Jai; Park, Jihun; Shin, Sungsik; Shin, Jung U.; No, Hyun; Lew, Dae Hyun; Yang, Woo Ick; Yun, Chae Ok; Lee, Kwang Hoon; Lee, Ju Hee

ArticleIssue Date2014CitationJournal of Dermatology, v.41, pp 65 - 65PublisherWILEY
Wnt Decoy Receptor (sLRP6E1E2) Induces Antifibrotic Effect Via Inhibition of Wnt Signaling in Keloid ScarsGo to Link

Lee, Jung-Sun; Lee, Won Jai; Yun, Chae-Ok

ConferenceIssue Date2013Citation16th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), pp.S53PublisherNATURE PUBLISHING GROUPPlaceUS; Salt Lake City, UT
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