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Synthesis of N-Hydroxyindole Derivatives via Pd-Catalyzed Electrophilic Cyclization

Authors
Oh, Soo MinShin, Seunghoon
Issue Date
Jun-2021
Publisher
WILEY-V C H VERLAG GMBH
Keywords
N-hydroxyindoles; Umpolung; Hydroxylamine; Electrophilic cyclization
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.42, no.6, pp.925 - 928
Indexed
SCIE
SCOPUS
KCI
Journal Title
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume
42
Number
6
Start Page
925
End Page
928
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/141834
DOI
10.1002/bkcs.12285
ISSN
0253-2964
Abstract
A synthetic protocol for the synthesis of C2-substituted N-hydroxyindoles has been developed which consists of Sonogashira coupling, partial reduction of the nitro group, and Larock cyclization. This protocol features superior generality and efficiency over conventional alternatives.
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COLLEGE OF NATURAL SCIENCES (DEPARTMENT OF CHEMISTRY)
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