한국 노인에서 단백질 섭취량과 신체활동이 노쇠 위험에 미치는 영향

Abstract

Frailty is characterized by increased vulnerability to stressors that puts older subjects at risk of developing adverse outcomes, including hospitalization, disability, and mortality. Protein intake and physical activity were strongly associated with low prevalence of frailty among elderly people. However, to our knowledge, there have been no cross-sectional studies examining the association between the combination of dietary protein intake and physical activity and risk of frailty in elderly people. The present study investigated the hypothesis that combination of dietary protein intake and physical activity was associated with risk of frailty. Three hundred and seventeen elderly people were recruited for this study. The participants were classified into two groups by Fried frailty criteria (frailty group, n=42, non-frailty group, n=275). Dietary intake, Mini Nutritional Assessment (MNA) and medical history were assessed. Frailty group had significantly higher age as compared to non-frailty group, while non-frailty group had significantly higher MNA score, intake of energy (kcal/day) and protein (g/kg/day) than frailty group. Multivariate logistic regression analysis showed that higher protein intake and physical activity was negatively associated with the risk of frailty after adjusting for the age, MNA score and energy intake. Also, a combination of higher Recommended Nutrition Intake (RNI) of dietary protein intake and recommended physical activity was negatively associated with the risk of frailty after adjusting for the age, MNA score and energy intake. The present study suggested that protein intake and physical activity are negatively associated with risk of frailty in elderly people. Also, a combination of higher RNI of dietary protein intake and recommended physical activity was strongly negatively associated with the risk of frailty in elderly people.