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Feasibility Study for the Monitoring of Urea in Dialysate Solution using Raman Spectroscopy

Authors
Kim, JaejinHwang, JinyoungKim, YongdanChung, Hoeil
Issue Date
Mar-2011
Publisher
WILEY-V C H VERLAG GMBH
Keywords
Urea; Hemodialysis; Intensity correction; Copper reflector; Raman spectroscopy
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.32, no.3, pp.805 - 808
Indexed
SCIE
SCOPUS
KCI
Journal Title
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume
32
Number
3
Start Page
805
End Page
808
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151329
DOI
10.5012/bkcs.2011.32.3.805
ISSN
0253-2964
Abstract
We have determined the urea concentration in an aqueous solution using Raman spectroscopy by incorporating a Teflon tube as an effective intensity correction standard as well as sample container. A non-overlapping Teflon band was used as the reference peak to correct Raman intensity variations that occasionally resulted from changes in laser power. To increase the sensitivity, we positioned a copper reflector inside the Teflon tube to maximize the collection of Raman scattering. The obtained accuracy using Raman spectroscopy was 0.53 mM, close to the range of accuracy of previous NIR studies (0.15-0.52 mM).
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