Improved motion-sensitized driven-equilibrium preparation for 3D turbo spin echo T-1 weighted imaging after gadolinium administration for the detection of brain metastases on 3T MRI
- Authors
- Lee, Sangjoon; Park, Dong Woo; Lee, Ji Young; Lee, Young-Jun; Kim, Taeyoon
- Issue Date
- 2016
- Publisher
- BRITISH INST RADIOLOGY
- Citation
- BRITISH JOURNAL OF RADIOLOGY, v.89, no.1063
- Indexed
- SCIE
SCOPUS
- Journal Title
- BRITISH JOURNAL OF RADIOLOGY
- Volume
- 89
- Number
- 1063
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/155532
- DOI
- 10.1259/bjr.20150176
- ISSN
- 0007-1285
- Abstract
- Objective:
To evaluate the clinical usefulness of an improved motion-sensitized driven-equilibrium (iMSDE) preparation for three-dimensional turbo spin echo (TSE) T1 weighted imaging after gadolinium administration in 3.0-T MRI for the detection of brain metastases compared with conventional gradient echo (C-GRE) T1 weighted imaging with gadolinium.
Methods:
40 patients with suspected brain metastases underwent MR studies, including two contrast-enhanced sequences, iMSDE-TSE and C-GRE. Post-enhancement images of 14 patients with suspected metastatic brain lesions were retrospectively analyzed, and comparisons between iMSDE-TSE and C-GRE were made using the Wilcoxon signed-rank test.
Results:
C-GRE detected 86 metastatic lesions, whereas iMSDE-TSE detected 97, including one false-positive lesion on both sequences. 11 of 96 metastases were detected on iMSDE-TSE only. On C-GRE, 15 of 85 metastases were equivocal. There was a significant difference between C-GRE and iMSDE-TSE in terms of the number of detected lesions (p = 0.024). Notably, the interobserver agreement for diagnosing metastases and identifying non-metastases was nearly identical. Overall, iMSDE-TSE achieves higher detectability of metastatic brain lesions, especially equivocal lesions.
Conclusion:
Compared with C-GRE, iMSDE-TSE detected more brain metastases. This method is especially helpful in discerning equivocal metastases.
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