Chitosan and its derivatives for gene delivery
- Authors
- Lee, Kuen Yong
- Issue Date
- Apr-2007
- Publisher
- SPRINGER
- Keywords
- chitosan; nanoparticle; gene delivery; targeting; siRNA
- Citation
- MACROMOLECULAR RESEARCH, v.15, no.3, pp.195 - 201
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- MACROMOLECULAR RESEARCH
- Volume
- 15
- Number
- 3
- Start Page
- 195
- End Page
- 201
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180261
- DOI
- 10.1007/BF03218774
- ISSN
- 1598-5032
- Abstract
- Non-viral vectors, including lipid- or polymer-based systems, have attracted much attention to date as a gene delivery vehicle, due to safety issues with viral vectors. Chitosan, a naturally existing cationic polymer, has shown great potential as a gene delivery carrier, as it has low immunogenicity and toxicity, excellent transcellular transport ability, and is relatively easy to chemically modify. This review summarizes and discusses the general features of chitosan and its applications as a delivery carrier of DNA and RNA.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 공과대학 > 서울 생명공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/180261)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.