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Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertensionopen access
- Authors
- Oh, Jaewon; Kim, Wonho; Kim, Gee-Hee; Kim, Hack-Lyoung; Park, Sang-Don; Min, Kyung Wan; Hyun, Dongkeun; Hong, Jun Hwa; Lim, Soo; Bae, Ji-Hwan; Shin, Jinho
- Issue Date
- Sep-2025
- Publisher
- SPRINGERNATURE
- Keywords
- Amlodipine; Hydrochlorothiazide; Olmesartan; Amlodipine; Antihypertensive Agents; Drug Combinations; Hydrochlorothiazide; Imidazoles; Olmesartan; Olmesartan Medoxomil; Tetrazoles; Amlodipine; Antihypertensive Agent; Hydrochlorothiazide; Imidazole Derivative; Olmesartan; Tetrazole Derivative; Adult; Aged; Blood Pressure; Combination Drug Therapy; Diagnosis; Drug Combination; Drug Effect; Drug Resistance; Drug Therapy; Female; Human; Hypertension; Male; Middle Aged; Pathophysiology; Treatment Outcome; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Tetrazoles; Treatment Outcome
- Citation
- JOURNAL OF HUMAN HYPERTENSION, v.39, no.9, pp 675 - 678
- Pages
- 4
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF HUMAN HYPERTENSION
- Volume
- 39
- Number
- 9
- Start Page
- 675
- End Page
- 678
- ISSN
- 0950-9240
1476-5527
- Abstract
- This pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.
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Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
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Related Researcher
- Shin, Jinho
- 서울 의과대학 (DEPARTMENT OF INTERNAL MEDICINE)