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A label-free single breast cancer cell detection using h-BN sandwiched MoS2 field-effect transistor combined with PDMS-constriction-channel

Authors
Lee, JusinYoon, YousangYang, HeewonAn, YoojeongSul, OnejaeLee, Su JaeLee, Seung Beck
Issue Date
Oct-2020
Publisher
Chemical and Biological Microsystems Society
Keywords
Cancer cell; Detection; Field-effect transistor; H-BN; Label-free; MDA-MB-231; MoS2; Single cell
Citation
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, pp.503 - 504
Indexed
SCOPUS
Journal Title
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Start Page
503
End Page
504
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/4434
Abstract
The electrical properties of MoS2 make it highly sensitive to the surface charge density of a cell on MoS2 channel. Here, we fabricated a h-BN sandwiched MoS2 FET integrated with a microfluidic PDMS-constriction-channel for the effective positioning and sensing of cancer cells. By combining advantages of sensitive electrical properties of 2D material and microfluidic geometry, our constriction-channel combined MoS2 sensor could distinguish a single breast cancer cell from the electrolyte by the positive threshold voltage shift of the sensor.
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서울 공과대학 > 서울 융합전자공학부 > 1. Journal Articles
서울 자연과학대학 > 서울 생명과학과 > 1. Journal Articles

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