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쇼그렌 증후군 환자에서 작은 침샘 조직검사의 진단적 효용성Diagnostic Effectiveness of Minor Salivary Gland Biopsy for Sjögren’s Syndrome

Other Titles
Diagnostic Effectiveness of Minor Salivary Gland Biopsy for Sjögren’s Syndrome
Authors
강보성김재욱
Issue Date
2015
Publisher
대한이비인후과학회 부산,울산,경남 지부회
Keywords
쇼그렌 증후군; 작은 침샘 조직검사; Sjögren’s syndrome; Minor salivary gland biopsy
Citation
임상이비인후과, v.26, no.2, pp 230 - 235
Pages
6
Journal Title
임상이비인후과
Volume
26
Number
2
Start Page
230
End Page
235
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/11077
DOI
10.35420/jcohns.2015.26.2.230
ISSN
1225-0244
2713-833X
Abstract
Background:Sjögren’s syndrome is difficult to diagnose. Because several tools for exact diagnosis have been made over the decades. However none of them is both sensitive and specific. American College of Rheumatology (ACR) issued new diagnostic criteria based on only three objective tests in 2012. These are immunoserologic test, minor salivary gland biopsy, ocular staining test. We analyzed diagnostic effectiveness of minor salivary gland biopsy in suggesting Sjögren’s syndrome patients based on ACR guideline. Methods:We analyze 41 patients who suggesting Sjögren’s syndrome retrospectively about Immunoserologic results, minor salivary gland biopsy results, ocular staining test. Sensitivity and specificity of minor salivary gland biopsy was obtained. Results:Minor salivary gland biopsy sensitivity was 70.8% and specificity, 100%, positive predictive value, 100%, negative predictive value, 70.8%. No salivary gland biopsy complication was noted in 41 patients. Conclusions:Minor salivary gland biopsy is objective test and keyword method for Sjögren’s syndrome final diagnosis. High specificity can help physician to exclude normal people from Sjögren’s syndrome patients. Due to relatively invasive procedure and low sensitivity, this procedure could be recommended to last step for final diagnosis.
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College of Medicine > Department of Otorhinolaryngology > 1. Journal Articles

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