Dosimetric effect of CT contrast agent in CyberKnife treatment plans
- Authors
- Kim, Hee Jung; Chang, Ah Ram; Park, Yang-Kyun; Ye, Sung-Joon
- Issue Date
- 18-Oct-2013
- Publisher
- BioMed Central
- Keywords
- CyberKnife; CT contrast; Small field beam
- Citation
- Radiation Oncology, v.8
- Journal Title
- Radiation Oncology
- Volume
- 8
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/13282
- DOI
- 10.1186/1748-717X-8-244
- ISSN
- 1748-717X
- Abstract
- Background: To investigate the effect of computed tomography (CT) contrast enhancement (CE) on the 3D dose distributions of non-coplanar small field beams in the CyberKnife (CK) treatment planning system (TPS) for the stereotactic ablative radiotherapy (SABR). Methods: Twenty-two pre-CE CT treatment plans were recruited to this retrospective plan study. Their post-CE CT plans were based on the pre-CE CT plan data and calculated using the same MU and beam paths in either Ray-Tracing or Monte Carlo (MC) algorithms. The differences in the doses of the beam path and the reference point between the pre- and post-CE CT plans were compared. The minimum, maximum, and mean doses in dose-volume histograms (DVHs) of target and organs-at-risk (OARs) were also compared. Results: The dose differences between the pre-and post-CE plans in a single beam path were less than 1.05% in both calculation algorithms, with respect to the prescription dose. At the center of the target volume, it was 1.9% (maximum 6.2%) in Ray-Tracing and 1.6% (maximum 4.0%) in MC. The CA effect showed on average 1.2% difference in the OAR maximum dose (maximum 7.8% in Ray-Tracing and 7.2% in MC). In the lung cases, the CT CE resulted in a dose difference of 2.4% (from 1.0% to 6.5%) without the calculation algorithm effect (maximum 20.3%). Conclusions: The CK treatment plan using the post-CE CT generally afforded less than 2% dose differences from the pre-CE CT plan. However, it could be up to 7.8% depending on the target positions in a body and be more than 20% with the calculation algorithms. Thus, the post-CE CT in CK treatment plans should be used with careful consideration for the CA effect, target position, and calculation algorithm factors.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Radiation Oncology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.