계피식물(Cinnamomum loureiroi)에서 분리한 coumarin과 유도체의 방오효과Antifouling Activity of Coumarin and its Derivatives Isolated from the Cinnamon Tree Cinnamomum loureiroi
- Other Titles
- Antifouling Activity of Coumarin and its Derivatives Isolated from the Cinnamon Tree Cinnamomum loureiroi
- Authors
- 김영도; 신현웅; 조지영
- Issue Date
- 2013
- Publisher
- 한국수산과학회
- Keywords
- Antifouling; Coumarin; Ulva pertusa; Navicula annexa; NMR
- Citation
- 한국수산과학회지, v.46, no.1, pp.53 - 58
- Journal Title
- 한국수산과학회지
- Volume
- 46
- Number
- 1
- Start Page
- 53
- End Page
- 58
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/14538
- ISSN
- 0374-8111
- Abstract
- The active antifouling compounds coumarin and its derivatives were isolated from the cinnamon tree Cinnamomum loureiroi . The antifouling activities were determined using representative soft fouling organisms: the seaweed Ulvapertusa and diatom Navicula annexa . The chemical constituents with antifouling activities were identified as coumarin, hydroxylcoumarin, coumaric acid, and cinnamaldehyde by interpreting nuclear magnetic resonance, and high-resolution mass spectroscopy data. These compounds were isolated from 1.09 g of crude Cinnamomum sp.methanol extract, yielding approximately 18.4, 6.3, 9.8, and 14.7 mg of coumarin, hydroxylcoumarin, coumaric acid, and cinnamaldehyde, respectively. The compounds inhibited U . pertusa zoospores with EC50 values of 0.13-0.25 μg/mL, and the diatom N . annexa with EC50 of 0.21-0.81 μg/mL.
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