Characterization of a new ScbR-like gamma-butyrolactone binding regulator (SlbR) in Streptomyces coelicolor
DC Field | Value | Language |
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dc.contributor.author | Yang, YH | - |
dc.contributor.author | Song, E | - |
dc.contributor.author | Kim, JN | - |
dc.contributor.author | Lee, BR | - |
dc.contributor.author | Kim, EJ | - |
dc.contributor.author | Park, SH | - |
dc.contributor.author | Kim, WS | - |
dc.contributor.author | Park, HY | - |
dc.contributor.author | Jeon, JM | - |
dc.contributor.author | Rajesh, T | - |
dc.contributor.author | Kim, YG | - |
dc.contributor.author | Kim, BG | - |
dc.date.available | 2018-05-10T05:28:44Z | - |
dc.date.created | 2018-04-18 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.issn | 0175-7598 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/12562 | - |
dc.description.abstract | gamma-Butyrolactones in Streptomyces are well recognized as bacterial hormones, and they affect secondary metabolism of Streptomyces. gamma-Butyrolactone receptors are considered important regulatory proteins, and various gamma-butyrolactone synthases and receptors have been reported in Streptomyces. Here, we characterized a new regulator, SCO0608, that interacted with SCB1 (gamma-butyrolactone of Streptomyces coelicolor) and bound to the scbR/A and adpA promoters. The SCO0608 protein sequences are not similar to those of any known gamma-butyrolactone binding proteins in Streptomyces such as ScbR from S. coelicolor or ArpA from Streptomyces griseus. Interestingly, SCO0608 functions as a repressor of antibiotic biosynthesis and spore formation in R5 complex media. We showed the existence of another type of gamma-butyrolactone receptor in Streptomyces, and this SCO0608 was named ScbR-like gamma-butyrolactone binding regulator (SlbR) in S. coelicolor. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.title | Characterization of a new ScbR-like gamma-butyrolactone binding regulator (SlbR) in Streptomyces coelicolor | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00253-011-3803-4 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.96, pp.113 - 121 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000308354300011 | - |
dc.identifier.scopusid | 2-s2.0-84866023402 | - |
dc.citation.endPage | 121 | - |
dc.citation.startPage | 113 | - |
dc.citation.title | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.volume | 96 | - |
dc.contributor.affiliatedAuthor | Kim, YG | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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