Melt crystallization of ibuprofen on surfaces patterned by a Nd : YAG laser
DC Field | Value | Language |
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dc.contributor.author | Chung, Jihae | - |
dc.contributor.author | Kim, Byung Jick | - |
dc.contributor.author | Chung, Haseung | - |
dc.contributor.author | Kim, Il Won | - |
dc.date.available | 2018-05-10T08:48:42Z | - |
dc.date.created | 2018-04-17 | - |
dc.date.issued | 2011-01 | - |
dc.identifier.issn | 0256-1115 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/13746 | - |
dc.description.abstract | Surface-based control of melt crystallization of ibuprofen (IBU) is reported. The substrates in the present study included glass, flat Au, and laser-patterned Au. The IBU crystal morphologies were regulated depending on the surfaces where IBU crystallization was induced, and spherical, sunflower-like, and dendritic morphologies were obtained. Especially, the dendritic morphology of a large surface area was observed on the novel laser-patterned surfaces. Three-dimensionally tortuous Au structures were achieved by a 532 nm Nd : YAG laser, of which Gaussian beam profile was reshaped into a flat-top contour using a custom-designed diffusing system. Also, the effect of poly-e-caprolactone was analyzed as a crystallization modulating additive to fine-tune the IBU crystal morphologies. The IBU crystallization behaviors as well as the laser patterning processes are described as a part of the ongoing efforts to develop a general strategy to utilize heterogeneous nucleation and directional growth to control the crystallization of important organic compounds, such as active pharmaceutical ingredients. | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | KOREAN JOURNAL OF CHEMICAL ENGINEERING | - |
dc.title | Melt crystallization of ibuprofen on surfaces patterned by a Nd : YAG laser | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s11814-010-0466-2 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF CHEMICAL ENGINEERING, v.28, no.1, pp.239 - 245 | - |
dc.identifier.kciid | ART001502512 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000285733700036 | - |
dc.identifier.scopusid | 2-s2.0-78650725001 | - |
dc.citation.endPage | 245 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 239 | - |
dc.citation.title | KOREAN JOURNAL OF CHEMICAL ENGINEERING | - |
dc.citation.volume | 28 | - |
dc.contributor.affiliatedAuthor | Kim, Byung Jick | - |
dc.contributor.affiliatedAuthor | Kim, Il Won | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Crystallization | - |
dc.subject.keywordAuthor | Ibuprofen | - |
dc.subject.keywordAuthor | Dendrite | - |
dc.subject.keywordAuthor | Laser | - |
dc.subject.keywordAuthor | Patterning | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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