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AIDS환자 치료를 위한 NvBAT 치료기법: RTI에 대한 PI의 우수성
- Authors
- 조남훈
- Issue Date
- 2007
- Publisher
- 대한전기학회
- Keywords
- AIDS; Non-Progressor; PI; Bifurcation Diagram; Lyapunov Stability1. 서 론† 교신저자; 正 會 員: 崇實大 工大 電氣工學部 助敎授工博 E-mail : nhjo@ssu.ac.kr接受日字 : 2007年 7月 4日最終完了 : 2007年 8月 21日HIV(Human Immunodeficiency Virus)는 CD4 수용체를 갖고 있는 T세포; 즉 보조T세포와 대식세포 등 면역세포를 공격하여 여러
- Citation
- 전기학회논문지ABCD, v.56, no.10, pp.1836 - 1843
- Journal Title
- 전기학회논문지ABCD
- Volume
- 56
- Number
- 10
- Start Page
- 1836
- End Page
- 1843
- ISSN
- 1229-2443
- Abstract
- - In this paper, we study the NvBAT treatment for AIDS patients that is combined with PI rather than RTI, while the previous results have been focused on the NvBAT in conjuction with RTI. To this end, we obtain a bifurcation diagram which shows a change in the equilibrium points, and in their stability properties as the PI drug effect is varied. Based on the bifurcation diagram, we show that the NvBAT can be combined with drug PI for the treatment of AIDS patients. Various computer simulation results are included, which show the superiority of the NvBAT with PI over that with RTI. Accordition to simulation result, the NvBAT combined with PI is able to keep virus load level lower than that combined with RTI, which is crucial to avoid the emergence of drug-resistant mutants. Moreover, it is shown that, for some AIDS patients, NvBAT with RTI cannot make patients into long term non-progressor, while NvBAT with PI can.
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Collections - College of Engineering > School of Electrical Engineering > 1. Journal Articles
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Related Researcher
- Jo, Nam Hoon
- College of Engineering (School of Electrical Engineering)