Recent Advances in Divergent Synthetic Strategies for Indole-Based Natural Product Libraries
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Taegwan | - |
dc.contributor.author | Ha, Min Woo | - |
dc.contributor.author | Kim, Jonghoon | - |
dc.date.accessioned | 2022-04-21T06:40:05Z | - |
dc.date.available | 2022-04-21T06:40:05Z | - |
dc.date.created | 2022-04-21 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | http://scholarworks.bwise.kr/ssu/handle/2018.sw.ssu/42176 | - |
dc.description.abstract | Considering the potential bioactivities of natural product and natural product-like compounds with highly complex and diverse structures, the screening of collections and small-molecule libraries for high-throughput screening (HTS) and high-content screening (HCS) has emerged as a powerful tool in the development of novel therapeutic agents. Herein, we review the recent advances in divergent synthetic approaches such as complexity-to-diversity (Ctd) and biomimetic strategies for the generation of structurally complex and diverse indole-based natural product and natural product-like small-molecule libraries. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MOLECULES | - |
dc.title | Recent Advances in Divergent Synthetic Strategies for Indole-Based Natural Product Libraries | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/molecules27072171 | - |
dc.type.rims | ART | - |
dc.identifier.bibliographicCitation | MOLECULES, v.27, no.7 | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000781452400001 | - |
dc.identifier.scopusid | 2-s2.0-85127923482 | - |
dc.citation.number | 7 | - |
dc.citation.title | MOLECULES | - |
dc.citation.volume | 27 | - |
dc.contributor.affiliatedAuthor | Kim, Jonghoon | - |
dc.type.docType | Review | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | natural products | - |
dc.subject.keywordAuthor | indole | - |
dc.subject.keywordAuthor | small-molecule library | - |
dc.subject.keywordAuthor | diversity-oriented synthesis | - |
dc.subject.keywordAuthor | complexity-to-diversity (Ctd) strategy | - |
dc.subject.keywordAuthor | biomimetic synthesis | - |
dc.subject.keywordPlus | DIVERSITY-ORIENTED SYNTHESIS | - |
dc.subject.keywordPlus | RING-DISTORTION STRATEGY | - |
dc.subject.keywordPlus | COMPOUND COLLECTION | - |
dc.subject.keywordPlus | DRUG DISCOVERY | - |
dc.subject.keywordPlus | ALKALOIDS | - |
dc.subject.keywordPlus | BIOLOGY | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.subject.keywordPlus | COMPLEX | - |
dc.subject.keywordPlus | IBOGA | - |
dc.subject.keywordPlus | VINCAMINE | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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