Retroduplication and loss of parental genes is a mechanism for the generation of intronless genes in Ciona intestinalis and Ciona savignyi
- Authors
- Kim, Dong Seon; Wang, Yao; Oh, Hye Ji; Choi, Dongjin; Lee, Kangseok; Hahn, Yoonsoo
- Issue Date
- Dec-2014
- Publisher
- SPRINGER
- Keywords
- Tunicate; Loss of intron; Retroduplication; Ciona
- Citation
- DEVELOPMENT GENES AND EVOLUTION, v.224, no.4-6, pp 255 - 260
- Pages
- 6
- Journal Title
- DEVELOPMENT GENES AND EVOLUTION
- Volume
- 224
- Number
- 4-6
- Start Page
- 255
- End Page
- 260
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11516
- DOI
- 10.1007/s00427-014-0475-y
- ISSN
- 0949-944X
1432-041X
- Abstract
- Tunicates, the sister clade of vertebrates, have miniature genomes and numerous intronless genes compared to other animals. It is still unclear how the tunicates acquired such a large number of intronless genes. Here, we analyzed sequences and intron-exon organizations of homologous genes from two closely related tunicates, Ciona intestinalis and Ciona savignyi. We found seven cases in which ancestral introns of a gene were completely lost in a species after their divergence. In four cases, both the intronless copy and the intron-containing copy were present in the genome, indicating that the intronless copy was generated by retroduplication. In the other three cases, the intron-containing copy was absent, implying it was lost after retroduplication. This result suggests that retroduplication and loss of parental genes is a major mechanism for the accumulation of intronless genes in tunicates.
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- Appears in
Collections - College of Natural Sciences > Department of Life Science > 1. Journal Articles
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