Isolation of antibacterial compounds from Parasenecio pseudotaimingasa
- Authors
- Cho, Eun Ju; Choi, Ji Yeon; Lee, Ki Ho; Lee, Sanghyun
- Issue Date
- Dec-2012
- Publisher
- KOREAN SOC HORTICULTURAL SCIENCE
- Keywords
- bacteria; extraction; fractionation; isolation; reflux; sterol
- Citation
- HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY, v.53, no.6, pp 561 - 564
- Pages
- 4
- Journal Title
- HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY
- Volume
- 53
- Number
- 6
- Start Page
- 561
- End Page
- 564
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/19992
- DOI
- 10.1007/s13580-012-0040-4
- ISSN
- 2211-3452
2211-3460
- Abstract
- The aim of this research was to investigate the antibacterial activity of Parasenecio pseudotaimingasa, a perennial plant belonging to the Asteraceae, tribe Senecioneae. The methanol extract, n-hexane fraction, and n-butanol fraction of P. pseudotaimingasa leaves all exhibited antibacterial activities against Escherichia coli and Staphylococcus aureus, forming inhibition zones greater than 11 mm in discs. Among them, the n-hexane fraction showed the highest antibacterial activity against E. coli and S. aureus, with an inhibition zone greater than 14 mm. Open-column chromatography was used to isolate the phytochemical constituents from the n-hexane fraction; spectroscopic analysis elucidated their structures as beta-sitosterol and daucosterol. Further testing of beta-sitosterol and daucosterol also revealed the antibacterial effects against both E. coli and S. aureus, suggesting their potential as antibacterial agents.
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Collections - College of Biotechnology & Natural Resource > ETC > 1. Journal Articles
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