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Preparation of a visible light-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) derivative and applicability as an anti-adhesion agent
- Authors
- Park, Shin-hye; Seo, Si-yoong; Na, Ha-na; Kim, Kwang-il; Lee, Jea-woo; Woo, Hee-dong; Lee, Jue-hee; Seok, Hyun-kwang; Lee, Jae-gwan; Chung, Sang-in; Chung, KyuHwan; Han, DongKeun; Ito, Yoshihiro; Jang, Eui-chang; Son, Tae-il
- Issue Date
- Sep-2011
- Publisher
- SPRINGER
- Keywords
- natural polymer; photo-reactive; anti-adhesion agent; carboxymethy chitsoan; water-soluble chitosan
- Citation
- MACROMOLECULAR RESEARCH, v.19, no.9, pp 921 - 927
- Pages
- 7
- Journal Title
- MACROMOLECULAR RESEARCH
- Volume
- 19
- Number
- 9
- Start Page
- 921
- End Page
- 927
- ISSN
- 1598-5032
2092-7673
- Abstract
- Photo-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) was synthesized by introducing a furfuryl group to the amine groups of LM-O-CMCS. The prepared photo-reactive LM-O-CMCS was characterized by FTIR, (1)H NMR, and a cross-linking test, whereas scanning Auger electron microscopy (SAM) and a MTT assay were used to confirm the cell viability. The water contact angle measurement and cell attachment test were carried out to determine the applicability of LM-O-CMCS as an anti-adhesion agent.
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