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마이크로파를 이용한 1-클로로-2-히드록시 할로히드린 유도체들의 합성Microwave Assisted Synthesis of 1-Chloro-2-hydroxy Halohydrin Derivatives
- Issue Date
- Dec-2006
- Publisher
- 중앙대학교 기초과학연구소
- Citation
- 기초과학연구소 논문집, v.20, pp 69 - 74
- Pages
- 6
- Journal Title
- 기초과학연구소 논문집
- Volume
- 20
- Start Page
- 69
- End Page
- 74
- Abstract
- Facile and efficient synthesis of 1-chloro-2-hydroxy haloydrin derivatives are newly developed. Reaction of epoxide with aluminum chloride hexahydrate under microwave irradiation conditions smoothly furnished 1-chloro-2-hydroxy halohydrin compounds in high yields in 90-120 sec reaction times. Along with regioselective reaction and environmentally friendly nature of the present protocol should serves as useful alternatives to the existing halohydrin formation by epoxide ring opening reactions.
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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