A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications
- Authors
- Jeong, Eun Ji; Chung, Sae Rom; Baek, Jung Hwan; Choi, Young Jun; Kim, Jae Kyun; Lee, Jeong Hyun
- Issue Date
- Mar-2018
- Publisher
- KOREAN ENDOCRINE SOC
- Keywords
- Thyroid nodule; Biopsy; fine-needle; Biopsy; large-core needle; Safety
- Citation
- ENDOCRINOLOGY AND METABOLISM, v.33, no.1, pp 114 - 120
- Pages
- 7
- Journal Title
- ENDOCRINOLOGY AND METABOLISM
- Volume
- 33
- Number
- 1
- Start Page
- 114
- End Page
- 120
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/45319
- DOI
- 10.3803/EnM.2018.33.1.114
- ISSN
- 2093-596X
2093-5978
- Abstract
- Background: To compare pain, tolerability, and complications associated with fine needle aspiration (FNA) versus core needle biopsy (CNB). Methods: FNAs were performed using 23-gauge needles and CNBs were performed using 18-gauge double-action spring-activated needles in 100 patients for each procedure. Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability. Complications and number of biopsies were recorded. Results: The median pain scores were similar for the FNA and CNB approaches during and 20 minutes after the biopsy procedures (3.7 vs. 3.6, P=0.454; 0.9 vs. 1.1, P=0.296, respectively). The procedure was tolerable in all 100 FNA patients and in 97 CNB patients (P=0.246). The mean number of biopsies was fewer in the CNB group (1.4 vs. 1.2, P=0.002). By subgroup analysis (staff vs. non-staff), no significant difference was detected in any parameter. There were no major complications in either group, but three patients who underwent CNB had minor complications (P=0.246). Conclusion: FNA and CNB show no significant differences for diagnosing thyroid nodules in terms of pain, tolerability, or complications.
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