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Evaluation of hydrophobic films for high sensitive and self aligning micro array protein chip

Authors
Lee J.-H.Lee M.Kang H.-B.Lim H.-W.Choo, JaebumPark J.-G.
Issue Date
Nov-2009
Publisher
Chemical and Biological Microsystems Society
Keywords
Hydrophobic; Micro array; Protein adsorption; Self align
Citation
Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp 235 - 237
Pages
3
Journal Title
Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Start Page
235
End Page
237
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/65153
ISSN
0000-0000
Abstract
Well plate based ELISA is one of the most widely used immunoassay techniques for the detection of a target protein. However, this method has some technical limits such as poor signal sensitivity, poor detection limit, large sample consumption, high evaporation rate, and low signal/noise ratio. In this paper, we fabricated a high sensitive pre-patterned micro array chip by using semiconductor process where chips have hydrophilic and hydrophobic patterns on a glass substrate. And we could acquire the high resolution scanning images on the microarray chip with hydrophobic patterning which has low protein adsorption. © 2009 CBMS.
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