High sensitization rate to food allergens in breastfed infants with atopic dermatitis
- Authors
- Han, Youngshin; Chung, Sang-Jin; Kim, Jihyun; Ahn, Kangmo; Lee, Sang-il
- Issue Date
- Oct-2009
- Publisher
- ELSEVIER SCIENCE INC
- Citation
- ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, v.103, no.4, pp 332 - 336
- Pages
- 5
- Journal Title
- ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Volume
- 103
- Number
- 4
- Start Page
- 332
- End Page
- 336
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/65189
- DOI
- 10.1016/S1081-1206(10)60533-9
- ISSN
- 1081-1206
1534-4436
- Abstract
- Background: The differences in the characteristics of breastfed and formula fed individuals with allergy have been addressed in few studies and remain controversial. Objective: To evaluate the effect of breastfed on the development of food allergy and sensitization against food allergens in infants with atopic dermatitis (AD). Methods: We reviewed 143 infants (77 boys and 66 girls) with AD who were younger than 6 months and were classified into the following 3 groups based on the type of feeding they received: breastfed, mixed feeding, and formula fed. All infants had never been fed egg or soy. The total and specific IgE levels were then assessed using a commercially available assay. Results: The total IgE level (P = .004) and egg specific IgE level (P = .002) were significantly higher in the BF group than in the FF group. The rate of sensitization to egg (P = .001) was also significantly higher in the BF group when compared with the FF group, as was the egg allergy rate (P = .004). Conclusion: Our results suggest that breastfeeding might not always be beneficial in allergy prevention in some high-risk infants. Ann Allergy Asthma Immunol. 2009; 103:332-336.
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