Effects of Dietary Conjugated Linoleic Acid and Biopolymer Encapsulation on Lipid Metabolism in Miceopen access
- Authors
- Sun Jin Hur; Doo Hwan Kim; Se Chul Chun; Si Kyung Lee
- Issue Date
- Apr-2013
- Publisher
- MDPI
- Keywords
- conjugated linoleic acid; biopolymers encapsulation; energy expenditure; adipose tissue; lipid metabolism
- Citation
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.14, no.4, pp 6848 - 6862
- Pages
- 15
- Journal Title
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Volume
- 14
- Number
- 4
- Start Page
- 6848
- End Page
- 6862
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/67730
- DOI
- 10.3390/ijms14046848
- ISSN
- 1661-6596
1422-0067
- Abstract
- Forty mice were randomly divided into four groups on the basis of the diet to be fed as follows: 5% (low) fat diet (T1: LF); 20% (high) fat diet (T2: HF); 20% fat containing 1% conjugated linoleic acid (CLA) (T3: HFC); and 20% fat containing 1% CLA with 0.5% biopolymers (T4: HFCB). The high-fat with CLA diet groups (HFC and HFCB) and the low-fat diet group (LF) tended to have lower body weights and total adipose tissue weights than those of the high-fat diet group (HF). Serum leptin and triglyceride were significantly lower in the high fat with CLA-fed groups (HFC and HFCB) and the low-fat diet group (LF) than those in the high-fat diet group (HF). It is noteworthy that the high-fat with CLA and biopolymers group (HFCB) showed the lowest serum triglyceride and cholesterol concentrations. In the high-fat-fed group (HF), voluntary travel distance as a measure of physical activity decreased after three weeks of feeding. However, the CLA-fed groups showed increased physical activity. The groups fed high-fat diets supplemented with CLA alone and with CLA and biopolymers had higher viscosity of small intestinal contents than that in the low-and high-fat dietary groups.
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