Nanomedicines for Therapy of Bladder Canceropen access방광암 치료를 위한 나노의약품
- Authors
- 송채은(Song Cheeun); 장승주(Jang Seung Ju); 전우혁(Jeon Woo Hyeok); 맹세정; 태종현; 장인호
- Issue Date
- 2022
- Publisher
- 대한비뇨기종양학회
- Keywords
- Bladder cancer; Nanoparticle; Intravesical instillation; Chemotherapy
- Citation
- 대한비뇨기종양학술지, v.20, no.4, pp 235 - 247
- Pages
- 13
- Journal Title
- 대한비뇨기종양학술지
- Volume
- 20
- Number
- 4
- Start Page
- 235
- End Page
- 247
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71092
- DOI
- 10.22465/kjuo.2022.20.4.235
- ISSN
- 2234-4977
- Abstract
- Bladder cancer is one of most common malignant urinary tract tumor types, and transurethral resection of nonmuscle invasive bladder cancer followed by intravesical instillation of immunochemotherapy is the standard treatment approach to minimize recurrence and delay progression of bladder cancer. In general, conventional intravesical immunochemotherapy lacks selectivity for tumor tissues and the effect of drug is reduced with the excretion of urine leading to frequent administration and bladder irritation symptoms. Recently, nanomedicines which adhere to the bladder tumors for a long time, and continuously and efficiently release drug to bladder cancers may overcome all the above problems. Moreover, the advances in nanomedicine based targeted therapy have led to significant improvements in drug efficacy and precision of targeted drug delivery. This review shows the available nano-systems of targeted drug delivery to bladder cancer tissues.
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