Fast and sensitive trace analysis of malachite green using a surface-enhanced Raman microfluidic sensor
- Authors
- Lee, Sangyeop; Choi, Junghyun; Chen, Lingxin; Park, Byungchoon; Kyong, Jin Burm; Seong, Gi Hun; Choo, Jaebum; Lee, Yeonjung; Shin, Kyung-Hoon; Lee, Eun Kyu; Joo, Sang-Woo; Lee, Kyeong-Hee
- Issue Date
- May-2007
- Publisher
- Elsevier BV
- Keywords
- microfluidic sensor; malachite green; surface-enhanced Raman spectroscopy; lab on a chip; trace analysis
- Citation
- Analytica Chimica Acta, v.590, no.2, pp.139 - 144
- Indexed
- SCIE
SCOPUS
- Journal Title
- Analytica Chimica Acta
- Volume
- 590
- Number
- 2
- Start Page
- 139
- End Page
- 144
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/43710
- DOI
- 10.1016/j.aca.2007.03.049
- ISSN
- 0003-2670
- Abstract
- A rapid and highly sensitive trace analysis technique for determining malachite green (MG) in a polydimethylsiloxane (PDMS) microfluidic sensor was investigated using surface-enhanced Raman spectroscopy (SERS). A zigzag-shaped PDMS microfluidic channel was fabricated for efficient mixing between MG analytes and aggregated silver colloids. Under the optimal condition of flow velocity, MG molecules were effectively adsorbed onto silver nanoparticles while flowing along the upper and lower zigzag-shaped PDMS channel. A quantitative analysis of MG was performed based on the measured peak height at 1615 cm(-1) in its SERS spectrum. The limit of detection, using the SERS microfluidic sensor, was found to be below the 1-2 ppb level and this low detection limit is comparable to the result of the LC-Mass detection method. In the present study, we introduce a new conceptual detection technology, using a SERS microfluidic sensor, for the highly sensitive trace analysis of MG in water. (c) 2007 Elsevier B.V. All rights reserved.
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Collections - COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY > DEPARTMENT OF MARINE SCIENCE AND CONVERGENCE ENGINEERING > 1. Journal Articles
- COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF BIONANO ENGINEERING > 1. Journal Articles
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