Detailed Information
Cited 2 time in 
Cited 2 time in 
Cited 2 time in
Metadata Downloads
Screening of Various Sources of Phytochemicals for Neuroprotective Activity against Oxygen-Glucose Deprivation in vitro
- Issue Date
- Aug-2013
- Publisher
- KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY
- Keywords
- cerebral cortical neuron; ischemia; neuroprotection; oxygen-glucose deprivation; phytochemical; taxol
- Citation
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.56, no.4, pp 451 - 455
- Pages
- 5
- Journal Title
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY
- Volume
- 56
- Number
- 4
- Start Page
- 451
- End Page
- 455
- ISSN
- 1738-2203
2234-344X
- Abstract
- Neuroprotective activities of 176 phytochemicals were investigated against oxygen-glucose deprivation in vitro using primary cortical neuron culture. Diterpenes (taxol and taxol C) were the most potent neuroprotective compounds. EC50 of taxol and taxol C were 0.402 and 0.452 mu M, respectively. This result supports the use of an in vitro model as initial screening for neuroprotective candidates, which warrants further testing in animal models.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > ETC > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.